Before having BRIVIACT, inform your healthcare provider about your whole health-related problems, including for those who:enasidenib will increase the stage or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Enasidenib (a weak CYP2C19 inhibitor) may boost systemic publicity of delicate CYP2C19 substrates.